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  • 标题:ASSESSMENT OF THE WHEATGRASS EFFECTS ON ANTIOXIDANT CAPACITY AND DNA DAMAGE IN RATS WITH EXPERIMENTAL RENAL FAILURE
  • 本地全文:下载
  • 作者:Leyla Mis ; Bahat Comba ; Yildiray Basbugan
  • 期刊名称:Fresenius Environmental Bulletin
  • 印刷版ISSN:1018-4619
  • 出版年度:2019
  • 卷号:28
  • 期号:4
  • 页码:2876-2879
  • 语种:English
  • 出版社:PSP Publishing
  • 摘要:In this study, it was aimed to evaluate the effect of wheatgrass on antioxidant capacity and DNA damage in rats with renal failure. In the study, 200-300 g 24 healthy Wistar -Albino male rats obtained from YYU Experimental Animal Unit were used. The rats were randomly divided into 4 groups and each group was formed with 6 rats. Groups were allocated as; 1. Control Group, 2. Renal Failure Group (Genta Group) 3. Renal Failure + Wheatgrass Group (Genta +Wheatgrass) 4. Wheatgrass Group. Gentamicin sulfate was given intraperitoneal at a dose of 50 mg/kg for 1 week and once a day to the groups with renal failure (Groups 2 and 3). Wheat grass extract (10 ml/kg) was added to the drinking water of the wheatgrass group rats (3rd and 4th groups) once a day. This practice lasted for 4 weeks. Total oxidant, antioxidant quantities, DNA damage were evaluated at the end of 4 weeks. The result that wheatgrass could be useful in renal failure was reached.
  • 关键词:Rat;TAS;TOS;Wheatgrass;Renal failure
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