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标题：Association between neighbourhood green space and biological markers in school-aged children. Findings from the Generation XXI birth cohort
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作者：Ana Isabel Ribeiro ; Carla Tavares ; Alexandra Guttentag 等
期刊名称：Environment International
印刷版ISSN：0160-4120
电子版ISSN：1873-6750
出版年度：2019
卷号：132
页码：1-9
DOI：10.1016/j.envint.2019.105070
语种：English
出版社：Pergamon
摘要：AbstractBackgroundThere is considerable literature on the psychological and behavioural benefits of green space. However, less is known about its health-promoting effects, as expressed on biological markers. Additionally, incorporating biomarkers into pediatric research may help elucidate the links between exposures to environmental stressors and lifelong health.ObjectiveTo measure the association between geographical accessibility to green spaces and allostatic load (AL), a measure of biological multi-system dysregulation.MethodsWe used data from 3108 7-year old children enrolled in Generation XXI, a population-based birth cohort from the Porto Metropolitan Area (Portugal). We computed an AL index based on seven biomarkers representing four regulatory systems: immune/inflammatory system (high sensitivity C-reactive protein); metabolic system (high density lipoprotein; total cholesterol; glycated hemoglobin; waist-hip ratio) and cardiovascular system (systolic and diastolic blood pressure). Accessibility to green spaces was calculated using a Geographic Information System and crude and adjusted associations were estimated using mixed-effects regression models.ResultsAmong the 3108 children (51.7% male; mean age 87.3 months), the mean AL index was 0.00 (standard deviation 2.94). Adjusted models showed that having a green space within 400 m and 800 m from the child's school was inversely associated with AL (400 m: beta −0.29 95% CI −0.54 to −0.02; 800 m: −0.29 95% CI −0.51 to −0.07). Also, there was a 12% (0%; 23%) increase in the AL index for every 1 km increase in distance to the nearest green space. No significant associations with AL were observed with residential accessibility to green space or with the presence of a garden at home.ConclusionWe found a cross-sectional negative association between accessibility to green space near schools and AL in children, suggesting that the provision of green space may contribute to improvements in population health beginning early in life.Highlights•Little is known about the health-promoting effects of green space on biomarkers.•We studied the association between green space accessibility and allostatic load.•Green space around schools lowers allostatic load in urban children.
关键词：Allostasis;Biomarkers;Neighbourhoods;Urban health;Nature;Portugal