文章基本信息

标题：Modulating Effects of Curcumin on Chromium Induced Chromosomal Aberrations in Somatic Cells of Mice
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作者：M. Moshe Raju ; K. Rudrama Devi
期刊名称：Nature, Environment and Pollution Technology
印刷版ISSN：0972-6268
出版年度：2010
卷号：9
期号：4
语种：English
出版社：Technoscience Publications
摘要：The protective effects of curcumin in chromium induced cytotoxicity was evaluated inin vivo animal model using analysis of chromosomal aberrations in somatic cells ofmice. Three doses of curcumin were selected for modulation and given to animalsafter priming with chromium. The animals ware sacrificed 48hr after the treatment andslides were prepared. A significant decrease was observed in the percentage ofchromosomal aberrations when animals were primed with curcumin. The presentresults clearly indicate the protective nature of curcumin against heavy metalgenotoxicity.