文章基本信息

标题：Sister Chromatid Exchanges in Peripheral Lymphocytes in Shoe Factory Workers Exposed to Organic Solvents
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作者：K. Rudrama Devi ; S. Jithender Kumar Naik
期刊名称：Nature, Environment and Pollution Technology
印刷版ISSN：0972-6268
出版年度：2011
卷号：10
期号：4
语种：English
出版社：Technoscience Publications
摘要：Shoe manufacturing is an age-old profession in India. The genotoxic potential of organic solvents in culturedperipheral lymphocytes has been investigated on 62 male workers in a leather shoe factory located at IDA,Nacharam in Ranga Reddy district of Andhra Pradesh by using one of the recommended cytogeneticbiomarkers. The blood samples were collected from male workers and 42 age matched controls. Analysis ofsister chromatid exchanges in human peripheral lymphocytes was carried out in control and exposed groups.A significant increase in the percentage of SCEs was observed as compared to control. Thus, the studyclearly reveals the mutagenic effect of organic solvents on human beings.