文章基本信息

标题：Synthesis of certain 8-quinolyloxy and/or carbocyclic nitrogenous compounds for microbiological testing
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作者：Khaled R.A. Abdellatif ; Madlen B. Labib ; Ossama M. El-Badry 等
期刊名称：Beni-Suef University Journal of Basic and Applied Sciences
印刷版ISSN：2314-8535
电子版ISSN：2314-8543
出版年度：2016
卷号：5
期号：2
页码：147-155
DOI：10.1016/j.bjbas.2016.02.005
语种：English
出版社：Elsevier
摘要：AbstractTwo new series as azosalicylic acid derivativesIVa-landVa-cin addition to three series containing 8-quinolyloxy moietyXa-i,XIIa-nandXIVa-ewere synthesized for evaluation as antimicrobial compounds. Structures of the newly synthesized compounds have been deduced on the basis of elemental analysis and spectral data. Antimicrobial activity evaluation was carried using agar dilution technique; there was variability in the susceptibilities of the different organisms to the tested compounds.Staphylococcus aureuswas the most resistant organism whileCandida albicanswas the most sensitive. Some compounds showed both antibacterial and antifungal activity, while others showed antibacterial activity with no antifungal activity and vice versa. CompoundXIVewas the most active against both bacteria and fungi, while compoundsXe,XIIf,XIVaandXIVdshowed a moderate activity.
关键词：8-Quinolyloxy moiety;Nitrogenous compounds;Antimicrobial activity