文章基本信息

标题：Testicular miRNAs in relation to spermatogenesis, spermatogonial stem cells and cancer/testis genes
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作者：Maryam Beigom Mobasheri ; Kehinde Adebayo Babatunde
期刊名称：Scientific African
印刷版ISSN：2468-2276
出版年度：2019
卷号：3
页码：1-8
DOI：10.1016/j.sciaf.2019.e00067
语种：English
出版社：Elsevier
摘要：AbstractThe process of spermatogenesis in human involves three organized biological processes, through which spermatogonia cells undergo mitosis, meiosis and finally differentiation into mature spermatozoa. Spermatogenesis requires a specifically regulated gene expression patterns. The microRNAs are a novel class of post-transcriptional regulators that have been reported to be involved in so many cellular processes including spermatogenesis, in which microRNAs are expressed in a stage-specific manner. Specific microRNAs are involved in the process of spermatogenesis and they have been identified to regulate and renew spermatogonia stem cell as well as been implicated in cancer biology regarding their effect in regulation of some of the cancer/testis genes.
关键词：KeywordsmiRNASpermatogenesisCancer/testis genesSpermatocytestesticular miRNAs