文章基本信息

标题：Chloroquine Resistance in a Case withUncomplicated Plasmodium vivaxMalaria: An Evolving Threat
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作者：Ganesh Kasinathan
期刊名称：Current Journal of Applied Science and Technology
印刷版ISSN：2457-1024
出版年度：2015
卷号：13
期号：2
页码：1-4
语种：English
出版社：Sciencedomain International
摘要：Introduction: Chloroquine resistance is an emerging phenomenon in uncomplicated Plasmodium vivax malaria.Presentation of Case: This case report describes a 21 year old forest worker who was diagnosed to have Plasmodium vivax malaria on blood film microscopy and it was confirmed on molecular real-time polymerase chain reaction analysis. He was treated with conventional oral chloroquine of optimal dosage in which he failed to respond appropriately. His blood film parasite count increased on day 3 of treatment despite adequate chloroquine therapy. He was then commenced on oral artemether-lumefantrine (Riamet) combination therapy in which he responded clinically and microscopically. He was discharged from the hospital after completing a 14-day course of oral primaquine. His serial blood films were negative for more than three consecutive days whilst in hospital. On subsequent weekly follow ups at the specialist clinic for a duration of 28 days, his blood films remained negative for malaria parasites.Conclusion: Chloroquine resistance is now an emerging threat in many middle and low income countries globally.
关键词：Chloroquine;malaria;Plasmodium vivax;hospital;microscopy