文章基本信息

标题：Different Protocols of Physical Training: Effect on Markers of Oxidative Stress in Erythrocytes in Rats
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作者：Marcelo Costa-Junior ; Wener Barbosa-Resende ; Michel Barbosa de Araújo 等
期刊名称：Open Access Library Journal
印刷版ISSN：2333-9705
电子版ISSN：2333-9721
出版年度：2018
卷号：5
期号：3
页码：1-4
DOI：10.4236/oalib.1104411
语种：English
出版社：Scientific Research Pub
摘要：The imbalance between oxidant molecules and antioxidant agents is characterized as oxidative stress (OS) and may lead to severe damage to the organism. In contrast, the physical training of aerobic and resistive character promotes increases of the antioxidant response, resulting in a balance and/or minimizing damage. Therefore, the objective of the study is to verify the effect of aerobic training, resistive training and concurrent training on oxidative stress of Wistar rats. Methods: To perform the experiment, 40 Wistar rats were subjected to eight weeks of training. The animals were distributed into 4 different groups: control, aerobic, resistive and concurrent (combination of aerobic and resistive protocols in the same section) an h/day, five days/week, for eight weeks. At the end of the experimental period: the antioxidant enzymes (catalase, glutathione peroxidase and superoxide dismutase), biomarkers of oxidative stress (TBARs and H2O2) as well as the activity of reduced and oxidized glutathione were analyzed. Results: Regarding the markers, TBARs and H2O2 trainings were not effective in promoting significant reduction. In contrast, the three training protocols caused an increase in SOD and GSH-GPx enzymes. Conclusion: Therefore, we concluded that both training protocols promoted benefit to the organism, because they caused the increase of antioxidant enzymes without disturbance in the pro-oxidant markers.
关键词：Oxidative StressExerciseAntioxidant Enzymes