文章基本信息

标题：NON-MUSCLE INVASIVE BLADDER CANCER RECURRENCERISK FACTORS
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作者：Octavian DRĂGOESCU ; Andrei Ioan DROCAȘ ; George MITROI 等
期刊名称：Research and Science Today
印刷版ISSN：2247-4455
电子版ISSN：2285-9632
出版年度：2016
期号：1
页码：139-146
语种：English
出版社：RST Journal
摘要：TO ESTABLISH THE RISK OF TUMORAL RECURRENCE FOR NON-MUSCLE INVASIVE BLADDER CANCER (NMIBC) DEPENDINGON HISTOLOGICAL OR ENVIRONMENTAL FACTORS. THE AIM OF THIS PAPER IS TO IMPROVE THE STANDARD CLINICAL CARE INNMIBC PATIENTS FOLLOW-UP.WE INITIALLY EVALUATED 987 PATIENTS DIAGNOSED WITH BLADDER CANCER BETWEENJANUARY 2005 AND DECEMBER 2014. MUSCLE-INVASIVE BLADDER CANCER (MIBC) WAS DIAGNOSED FOR 309 PATIENTS(31.3%) WHILE 678 (68.7%) HAD NMBIC. A TOTAL OF 540 PATIENTS WITH NMIBC WERE ANALYZED IN THE STUDY, WHILETHE OTHER 138 (20.4%) WERE EXCLUDED DUE TO INCOMPLETE CLINICAL DATA OR FOLLOW-UP. THE RETROSPECTIVE STUDYANALYZED PATIENTS’ CHARTS, DISCHARGE NOTES, ONCOLOGY REPORTS. PATIENTS WITH AT LEAST 3 YEARS COMPLETEFOLLOW-UP DATA WERE ENROLLED.THE AVERAGE AGE OF DIAGNOSED PATIENTS WITH NMIBC WAS 65.3 YEARS. THEMAJORITY OF PATIENTS WERE DIAGNOSED WITH SINGLE TUMORS (68.5%). NMIBC WAS PREDOMINANT IN MALES, WITH A SEXRATIO 3.25:1 FOR MALES. BLADDER TRIGON IS THE MAIN LOCATION FOR BLADDER TUMORS. SMOKING WAS THE MAIN RISKFACTOR ACCORDING TO OUR RESULTS. SMOKERS HAD A 4 TIMES HIGHER RISK FOR NMIBC DEVELOPMENT. PATIENTS WITHMULTIPLE BLADDER TUMORS HAD 2.28 HIGHER RISK OF RECURRENCE. OVERALL RECURRENCE FOR NMIBC WAS49.1%.SMOKING IS THE MOST IMPORTANT RISK FACTOR AND THE RECURRENCE RATE IS HIGHER IN SMOKING-PATIENTS.ALSO,PATIENTS WITH MULTIPLE TUMOURS HAVE BEEN DIAGNOSED WITH HIGHER RISK FOR TUMOR RECURRENCE (P<0.05). LARGETUMORS AND PATIENTS WITH ASSOCIATED UROLOGICAL CONDITIONS HAVE HIGHER RISK OF TUMORAL RECURRENCE (OR=2.2).
关键词：RECURRENCE;BLADDER CANCER;PROGRESSION;RISK FACTORS