文章基本信息

标题：Zinc exposure for female workers in a galvanizing plant in Northern Italy
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作者：Matteo Riccò ; Matteo Riccò ; Silvia Cattani 等
期刊名称：International Journal of Occupational Medicine and Environmental Health
印刷版ISSN：1232-1087
电子版ISSN：1896-494X
出版年度：2018
卷号：31
期号：1
页码：113-124
DOI：10.13075/ijomeh.1896.00878
语种：English
出版社：Walter de Gruyter GmbH
摘要：Objectives Very little is known regarding the toxicokinetics of inhaled zinc, in particular in the case of female workers and for modern, low exposure settings. Our aim is to evaluate the relationship of external zinc levels to those of serum and urine for female workers. Material and Methods Eleven female workers (age: 41.7±8 years old, body mass index (BMI): 23.5±4.2 kg/m 2 ) in a galvanizing plant were investigated. Exposure assessment consisted of personal/environmental air samples, and measurement of zinc in serum (collected at the end of first shift of the working week (T1)) and urine, collected before the first shift of the working week (T0), T1 and at the end of the last shift of the working week (T2). Results Both environmental and personal air samplings for zinc and zinc compounds were below the recommended by the German Research Foundation (Deutsche Forschungsgemeinschaft – DFG) limit values of 2 mg/m 3 (7.34±2.8 μg/m 3 and 8.31±2.4 μg/ m 3 , respectively). Serum (118.6±20.9 μg /dl) and urine zinc levels were within reference values for female Italian subjects: the latter increased from 56.4±33.5 μg/dl at T0, to 59.8±37.0 μg/dl at T1, and ultimately 65.4±34.4 μg/dl at T2, but no significant trend was found. End of shift (Spearman’s correlation coefficient p value = 0.027) and differential excretion of urinary zinc (both: T0 vs. T1 and T0 vs. T2) were correlated with airborne zinc concentration (p = 0.002 and 0.006, respectively). Conclusions In general, our data suggests that urine may be a useful medium also for female in order to assess zinc exposure. Further studies are required in order to evaluate whether differential excretion may be useful for the biomonitoring of zinc exposure in the workplaces also for male workers. Int J Occup Med Environ Health 2018;31(1):113–124