文章基本信息

标题：Wearable sensor-based data analysis for neurological disease symptoms evaluation utilising quantitative approach.
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作者：Mariusz Chmielewski ; Michał Nowotarski
期刊名称：MATEC Web of Conferences
电子版ISSN：2261-236X
出版年度：2018
卷号：210
DOI：10.1051/matecconf/201821005015
语种：English
出版社：EDP Sciences
摘要：The paper describes implementation of an analytical method and conclusions of novel approach to clinical trials monitoring and evaluation. Based on clinical trials observations a set of requirements for validating symptoms of neurological diseases have been formulated, concentrating on the ones which can be registered using wearable sensors. The constructed tool utilizes conventional surveying methods supplemented with biomedical sensor for neurological symptoms recognition and intensity evaluation. Developed mobile system is aimed at clinical trials assistance utilising sensor-based state evaluation. Such quantitative approach is a supplement for patient’s subjective evaluation of health state. This work is a discussion on pros and cons of such process composition and its supplementation with technology. Existing methodology relies on health state evaluation based on iteratively answered questionnaires, which in our understanding cannot be fully controlled and reliable. Utilisation of actigraphy and electromyography provides efficient means of some gestures recognition but most of all PD tremor identification and evaluation of their intensity, therefore can be used for ON/OFF state and dyskinesia identification and evaluation. In order to recognise specific states for PD patients (tremors, bradykinesias, rigidity, mental slowness, etc.) a set of additional techniques have been designed and implemented.