摘要:AbstractThis study aims to determine the ability of cooperation and communication student by applying a chemo-entrepreneurship learning approach. This study was conducted to the students of secondary school that uses descriptive analysis method. The ability of cooperation and communication of the students was assessed using three assessment instruments, self-report; peer review and observation sheets. They are made based on seven indicators, be responsible of the task; create a conducive atmosphere during the discussion; take part in decision-making; respect the opinions and decisions of the group; express ideas clearly and effectively; choose suitable words and the good intonation; respond to other interlocutors positively. The results of this study indicate that chemo-entrepreneurship approach (CEP) can be applied to improve the ability of student's cooperation and communication.