文章基本信息

标题：Model Free Control for Type-1 Diabetes: A Fasting-Phase Study ∗
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作者：Taghreed Mohammad Ridha ; Claude H. Moog
期刊名称：IFAC PapersOnLine
印刷版ISSN：2405-8963
出版年度：2015
卷号：48
期号：20
页码：76-81
DOI：10.1016/j.ifacol.2015.10.118
语种：English
出版社：Elsevier
摘要：AbstractIn this work the problem of regulating glycemia of Type-1 Diabetes(TlD) is investigated. Model-free control (Intelligent PID or iPID) is employed for the first time as a control algorithm to close the loop of the artificial pancreas. It is tested in silico employing a novel long-term model of the glucose-insulin dynamics of T1D evaluated on clinical data of several patients from two university hospital centers in France. Among closed-loop glycemia regulation studies, many have focused on stabilizing overnight/fasting glycemia due to the risk of overnight hypoglycemia. Thus, the first concern is to test iPID control on virtual patients during overnight and fasting (non-glucidic regime) phase. Changing only one control parameter from one patient to another, the results show that iPID outperformed the existing open-loop Functional Insulin Therapy (FIT) based control without hypoglycemic risk
关键词：KeywordsBiomedical controltype-1 diabetesartificial pancreasmodel-free controlintelligent PIDalgebraic estimation