摘要:AbstractDrug addiction is one of the social problems that not only creates psychological and social problems for the addict, but also creates problems for their families. Considering the socio-economical and psychological problems that follow addiction in a society, identification of effective factors responsible for addiction, especially from the wives of addicts viewpoint who ar e the closest members to the affected in comparison to others in the family is very important. This descriptive cross-sectional study was conducted using a special questionnaire and included 261 spouses of addicts referring to the detoxification centers of Yazd city who were selected randomly. The results showed that from the wives of addicts viewpoint, easy access to drugs was the most important factor responsible for addiction (Mean score of 4.42 +/-0.83 from a total score of 5). The other important factors were addicted friends and inability of the person to refuse when invited to use drugs by acquaintances (Mean scores of 4.41 +/-0.84 and 4.35+/- 0.92, respectively). Control of surrounding factors and an increase in self esteem are two important factors that can help effectively control addiction in the young population. After addiction, though environmental and surrounding factors play a role in preventing return to addiction, their role is reduced.