文章基本信息

标题：A spectroscopic study on the effect of ultra-violet solar radiation in Antarctica on the human skin fibroblast cells
本地全文：下载
作者：Tatsuyuki Yamamoto ; Hideo Akiyoshi ; Keisuke Yoshikiyo 等
期刊名称：Geoscience Frontiers
印刷版ISSN：1674-9871
出版年度：2013
卷号：4
期号：6
页码：647-653
DOI：10.1016/j.gsf.2012.07.004
语种：English
出版社：Elsevier
摘要：AbstractA study on the effect of the solar ultra-violet radiation on the human skin fibroblast cells revealed that the production of matrix metalloproteinase-2 was inhibited by the radiation. A CO2incubator connected by optical fibers to a reflector telescope for collecting the solar light was built at Syowa station by the 49th Japanese Antarctica Research Expedition. The direction of the telescope was continuously controlled by a sun-tracker to follow the movement of the Sun automatically. The intensity of the collected light was monitored by a portable spectrophotometer housed inside. The human skin fibroblast cells were incubated in the CO2chamber to investigate the effect of the solar radiation at Syowa station and were compared with those reference experiments at a laboratory in Japan. The results showed cell damage by strong UV radiation. The production of matrix metalloproteinase-2 was prompted by the moderate UV-B, but was inhibited by the strong UV-B radiation, as studied under laboratory conditions in Japan. The effect of strong solar radiation at Syowa station involving the radiation of UV-B region was estimated to be of the same extent of the radiation caused by an artificial UV-B light with the intensity more than 50 mJ/cm2.Graphical abstractDisplay OmittedHighlights► The effect of solar ultra-violet radiation in Antarctica on the human skin fibroblast was studied. ► The direction of the telescope was continuously controlled by a sun-tracker to follow the Sun. ► The production of MMP-2 was prompted by the moderate UV-B, but inhibited by the strong UV-B radiation.
关键词：KeywordsenAntarcticaGeobiologyUltra-violet radiationHuman skin fibroblast cellsMatrix metalloproteinase