文章基本信息

标题：The Relation Between Physiological Markers of Cardiovascular Health and Quality of Life in Heart Failure
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作者：Luke S. Acree ; Luke S. Acree ; Charles B. Porter 等
期刊名称：Journal of exercise physiology online
印刷版ISSN：1097-9751
出版年度：2012
卷号：15
期号：6
页码：13-22
语种：English
出版社：American Society of Exercise Physiologists
摘要：Acree LS, Porter CB, Godard MP. The Relation Between Physiological Markers of Cardiovascular Health and Quality of Life in Heart Failure. JEPonline 2012;15:13-22. This cross-sectional study examined the associations among functional capacity, ejection fraction, and health-related quality of life (HRQoL) in stable heart failure patients. Twenty-one stable NYHA Class II and III heart failure patients (mean age = 56.9 ± 11.1 yrs; BMI = 28.9 ± 4.2 kg·m -2 ) participated in this study. The subjects underwent cardiopulmonary treadmill testing to determine peak oxygen consumption (VO2 peak = 16.9 ± 5.3 mL·kg-1 ·min-1 ) and ventilatory threshold (961.9 ± 308.4 ml). The Kansas City Cardiomyopathy Questionnaire (KCCQ) was used to assess HRQoL. Ejection fraction was assessed by echocardiogram (EF = 28.9 ± 8.03%). HRQoL was non-significantly (P>0.05) related to VO2 peak (r = 0.221), EF (r = 0.204), and ventilatory threshold (r = 0.108). However, the physical limitation domain of the KCCQ was independently related (P<0.05) to VO2 peak (r = 0.621) and ventilatory threshold (r = 0.555). The physiological markers of cardiovascular health were specifically related to the physical limitations domain of the KCCQ. These same markers, however, were not associated with overall HRQoL, which suggest that both quantitative and qualitative measures may be used to better assess cardiovascular health in heart failure patients.
关键词：Exercise;VO2 Peak;Ejection Fraction;Echocardiogram