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标题：Long Term Running Exercise vs. Long Term Strength Exercise on Femoral Bone Mass Assessed in a Rat Model
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作者：Romeu Rodrigues De Souza ; Romeu Rodrigues De Souza ; Maria Do Carmo Sitta 等
期刊名称：Journal of exercise physiology online
印刷版ISSN：1097-9751
出版年度：2013
卷号：16
期号：2
页码：92-98
语种：English
出版社：American Society of Exercise Physiologists
摘要：De Souza RR, Sitta MC, Santarem Sobrinho JM, Jacob Filho W. Long Term Running Exercise vs. Long Term Strength Exercise on Femoral Bone Mass Assessed in a Rat Model. JEPonline 2013;16(2):92-98. This study evaluated the efficacy of long term running exercise compared to long term strength training for enhancing bone mineral density (BMD) in male rats. Ten Wistar rats aged 3 mth were submitted to running exercise (RE group) for 1 hr·d -1 , 3 days a week on a motor-driven treadmill at 16 m·min-1 . Addition 10 male rats (SE group) were submitted to strength exercise that was performed 3 d·wk-1 that consisted of climbing a 1.1 m vertical (80° incline) ladder with weights tied to their tail. In both groups, the training level was maintained for 15 mth. All rats were sacrificed at 18 mth of age. Sedentary age-matched rats served as controls (CO group, n = 10). At death the right femur was obtained from each rat and the Bone Mass Density (BMD) of the femur was measured using a dual-energy X-ray absorptiometry. The BMD measurements revealed a significant training-induced increase in global BMD in both the SE and the RE groups with 18 mth of age when compared to the CO (P<0.05). Significant difference in BMD was found between SE and RE groups (P<0.05). The BMD was higher in the SE compared to the RE. In conclusion, the long-term running exercise and the long term strength exercise have a positive effect on femoral neck bone mass in aging rats. The findings demonstrate the potential therapeutic effect of the two types of exercise in protecting against osteoporotic fractures later in life.
关键词：Physical Activity;Bone Mass;Femur;Aged Rat