文章基本信息

标题：Use of Hyaluronic Acid–Based Biological Bilaminar Matrix in Wound Bed Preparation: A Case Series
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作者：Richard Simman ; Richard Simman ; Walid Mari 等
期刊名称：ePlasty: Open Access Journal of Plastic and Reconstructive Surgery
印刷版ISSN：1937-5719
出版年度：2018
卷号：18
语种：English
出版社：Open Science Co. LLC
摘要：Objective:Hyalomatrix, a matrix that consists of esterified hyaluronic acid, covered with a removable, semipermeable silicone top layer, was used to generate granulation tissue in a series of 12 serious, surgical wounds of different etiologies.Methods:Many defects showed exposed muscle, tendons, and/or bone. After thorough debridement, the matrix was applied, in a number of cases, combined with negative pressure wound therapy.Results:All wounds developed granulation tissue in and on top of the matrix. Nine wounds were then closed with a split skin autograft. There was no graft failure, and all wounds showed complete reepithelialization. Three wounds healed by secondary intention and also reached complete healing.Conclusion:This case series shows a strong trend for Hyalomatrix to play an important role in supporting wound healing in complex, surgical wounds.