文章基本信息

标题：On-Set of Cataract and Accumulation of Copper, Lead and Cadmium in Smokers of Karachi, Pakistan
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作者：Anzar Ahmad ; Imtiaz Ahmad ; Moazzam A Khan 等
期刊名称：Journal of Environmental & Analytical Toxicology
电子版ISSN：2161-0525
出版年度：2015
卷号：5
期号：2
DOI：10.4172/2161-0525.1000252
语种：English
出版社：OMICS International
摘要：Background: High prevalence of cataract especially in women, children and urban dwellers and associated blindness is a major problem of Pakistan and low and middle income countries. Prevalence of tobacco use is also very high in Pakistan. The aim of study was to identify association between cigarette smoking and development of cataract in people of Karachi and to determine effect of Lead, Cadmium and Copper in progression of Cataract Material and methods: 100 Cataract Patients including Smokers and Non-Smokers visiting LRBT Hospital. Karachi was selected randomly. After Surgical Removal, their lenses were analyzed for Cadmium, Lead and Copper Concentration by Atomic Absorption Spectrometer at Pakistan Council of Scientific and Industrial Research Results: Concentration of Cadmium, Lead and Copper were found to be significantly higher among Lenses of Smokers than Non-Smokers. Conclusion: Cataract development occurred earlier in heavy smokers with mean age 48.24 years as compared to non-smokers mean age 55.72 years along-with increased accumulation of Cadmium, Lead and Copper in their lenses. The result shows an association between Cigarette Smoking and progression of Cataract
关键词：Cigarette Smoking; Cataract; Tobacco; DNA; Cadmium