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标题：Enterobacteriaceae Sepsis Outcome Programme annual report, 2013
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作者：John D Turnidge ; Thomas Gottlieb ; David H Mitchell 等
期刊名称：Communicable Diseases Intelligence
印刷版ISSN：1447-4514
电子版ISSN：1445-4866
出版年度：2014
卷号：38
期号：4
页码：E327-E333
出版社：Government Department of Health and Ageing
摘要：The Australian Group on Antimicrobial Resistance performs regular period-prevalence studies to moni- tor changes in antimicrobial resistance in selected enteric Gram-negative pathogens. The 2013 survey focussed for the first time on blood stream infec- tions. Four thousand nine hundred and fifty-eight Enterobacteriaceae species were tested using com- mercial automated methods (Vitek. 2, BioMérieux; Phoenix., BD). The results were analysed using Clinical and Laboratory Standards Institute (CLSI) and European Committee on Antimicrobial Susceptibility Testing (EUCAST) breakpoints (January 2014). Of the key resistances, non-susceptibility to the third- generation cephalosporin, ceftriaxone, was found in 7.5%/7.5% (CLSI/EUCAST criteria respectively) of Escherichia coli; 6.3%/6.3% of Klebsiella pneumo- niae, and 7.4%/7.4% of K. oxytoca. Non-susceptibility rates to ciprofloxacin were 10.3%/11.3% for E. coli, 4.6%/7.5% for K. pneumoniae, 0.6%/0.6% for K. oxytoca, and 3.6%/6.1% in Enterobacter cloacae. Resistance rates to piperacillin-tazobactam were 3.1%/6.2%, 4.2%/7.0%, 11.9% /12.6%, and 17.3% /22.2% for the same 4 species respectively. Fourteen isolates were shown to harbour a carbapenemase gene, 9 bla IMP , 3 bla KPC , and 2 bla NDM .
关键词：antibiotic resistance; bacteraemia; ; gram-negative; Escherichia coli; Enterobacter; ; Klebsiella