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标题：Larvicidal and pupicidal activity of synthesized silver nanoparticles using Leucas aspera leaf extract against mosquito vectors, Aedes aegypti and Anopheles stephensi
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作者：S. Sivapriyajothi ; P. Mahesh Kumar ; K. Kovendan 等
期刊名称：Journal of Entomological and Acarological Research
印刷版ISSN：2038-324X
电子版ISSN：2279-7084
出版年度：2014
卷号：46
期号：2
页码：77-84
DOI：10.4081/jear.2014.1787
语种：English
出版社：PAGEPress Publications
摘要：Mosquitoes are one of the most medically significant groups of vectors, having an ability to transmit parasites and pathogens that can have devastating impacts on humans. The development of reliable and ecofriendly processes for the synthesis of metallic nanoparticles is an important step in the field of application of nanotechnology. In this study, we address the biosynthesis of silver nanoparticles (AgNPs) using Leucas aspera leaf extract, and evaluate its lethal concentration (LC 50 and LC 90 ) values against first to fourth instar larvae and pupae of the mosquito vectors, Aedes aegypti and Anopheles stephensi . The nanoparticles were characterized by UV-Vis spectrum, scanning electron microscopy, energy-dispersive X-ray spectroscopy, and Fourier-transformed infrared spectroscopy analysis. Larvae and pupae were exposed to varying concentrations of aqueous extracts of synthesized AgNPs for 24 h. The maximum mortality was observed from synthesized AgNPs, with LC 50 values for I-IV instars and pupae ranging from 13.06 to 25.54, and LC 90 values ranging from 24.11 to 47.34 for A. aegypti ; for A. stephensi , the corresponding LC 50 values ranged from 12.45 to 22.26, and the LC 90 values ranged from 23.50 to 42.95. With methanol leaf extract of L. aspera against A. aegypti , the LC 50 values ranged from 174.89 to 462.96 and the LC 90 values ranged from 488.16 to 963.74; for A. stephensi , the corresponding LC 50 values ranged from 148.93 to 417.07 and the LC 90 values ranged from 449.72 to 912.94. The study suggests that nanoparticles could be a preferred alternative to the most hazardous existing chemical pesticides, contributing to a more healthy environment by providing an ideal ecological and user-friendly vector control strategy for managing malaria and dengue, and contributing to their eventual elimination in the near future.
关键词：Aedes aegypti; Anopheles stephensi; Leucas aspera; larvicidal activity; silver nanoparticles.