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  • 标题:Decision Support Models and Software for the Differential Immunophenotype Diagnostics of Leukosis and Lymphomas/ Lēmumu pieņemšanas modeļi un programmnodrošinājums diferenciālajai imūnajai fenotipiskajai leikožu un limfomu diagnostikai/ Модели принятия решений и программное обеспечение для дифференциальной иммунофенотипической диагностики лейкозов и лимфом
  • 作者:Natalia Novoselova ; Igor Tom ; Michael Belevtsev
  • 期刊名称:Information Technology and Management Science
  • 印刷版ISSN:2255-9086
  • 电子版ISSN:2255-9094
  • 出版年度:2014
  • 卷号:17
  • 期号:1
  • 页码:9-18
  • DOI:10.1515/itms-2014-0001
  • 语种:English
  • 出版社:Walter de Gruyter GmbH
  • 摘要:This article describes the software and underlined decision support models for the immunophenotype diagnostics of leukosis (leukemia) and lymphomas adjusted for the marker or human leukocyte antigen (CD-antigen) coexpressions. Using the model knowledge base, the decision inference algorithm allows computing the degree of manifestation of the disease subtypes for the input immunophenotype features. Software provides the twostage diagnostics of the leukemia subtypes and the lymphoma diagnostics using the set of the developed rules, possibility to observe the diagnostic results and corresponding reference information. The patient data are organized according to the unified registration card, which provides the possibility to work at the different diagnostic levels: diagnostics of the extended groups of leukosis, diagnostics of the leukemia subtypes, diagnostics of the adult and child lymphomas.
  • 关键词:Diagnostic rules ; decision support ; immunophenotyping ; modeling
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