文章基本信息

标题：Design of MDIs for Type 1 Diabetes Treatment via Rolling Horizon Cardinality-Constrained Optimisation
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作者：Diego S. Carrasco ; Aaron D. Matthews ; Graham C. Goodwin 等
期刊名称：IFAC PapersOnLine
印刷版ISSN：2405-8963
出版年度：2017
卷号：50
期号：1
页码：15044-15049
DOI：10.1016/j.ifacol.2017.08.2516
语种：English
出版社：Elsevier
摘要：AbstractRecent results on cardinality constrained optimisation are used to obtain an optimised Multiple Daily Injection (MDI) insulin regimen for Type 1 Diabetes patients. The optimisation is implemented in a rolling horizon fashion to account for unannounced events. A blood glucose model is described and an algorithm developed to illustrate the aforementioned strategy. The impact of varying the number of allowable injections in a given day is also studied. Real patient data is used to obtain the models and simulation results are included.
关键词：Keywordsoptimisationdiabetesblood glucose regulation