文章基本信息

标题：A model for controlled dosing of femto-litre volume liquids using hollow microcantilever
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作者：Xi Cao ; Rick de Gruiter ; Ralph van Oorschot 等
期刊名称：IFAC PapersOnLine
印刷版ISSN：2405-8963
出版年度：2017
卷号：50
期号：1
页码：15542-15547
DOI：10.1016/j.ifacol.2017.08.2141
语种：English
出版社：Elsevier
摘要：AbstractA hollow microcantilever is used instead of a conventional microcantilever to dispense and aspirate liquids in the femto-litre (10-15L) volume range in an atomic force microscope (AFM) setup. The inherent force sensing capability of the cantilever is used to monitor the fluid manipulation in-situ. At this small scale, parameters like: surface energy, evaporation, viscosity and temperature become important for controlled manipulation. In a conventional AFM, these parameters are usually not taken into consideration as feedback parameters. In the present work, we report initial experimental results on the dosing process and an analytical dynamic model of the process. The model is based on the liquid bridge between the cantilever tip and the substrate, which can describe the dosing process with variance accounted for (VAF) larger than 90%. We aim to use this model and implement a control system for precise dispensing and aspiration.
关键词：Keywordsdynamic modellinghollow-cantilevernanotechnologyfemto-literAtomic Force Microscope