摘要:Abstract Aim Coronary Artery disease as a chronic disease is the single largest killer of people in the worldwide. Despite advances in medical treatment, CAD is still associated with high morbidity, mortality, high hospitalization rates. Patients with CAD require comprehensive rehabilitation to control symptoms, slow the progressive nature of condition, decrease re hospitalization, and improve survival. To achieve these outcomes, patient adherence to prescribed medications is vital whereas Poor adherence to the long-term treatment of chronic diseases has been a growing problem and a major challenge for health care professionals. The purpose of this study was to test the efficacy of The Chronic ِ Disease Self Management Rehabilitation Programs and Tele- health in cardiac patients undergone Coronary Artery Bypass Surgery (CABGS), in order to improve, enhance and maintain their adherence by increasing the efficacy during intervention sessions. Method A total of 300 patients, were recruited through Tehran Heart Center's cardiac rehabilitation clinic. They were randomly assigned to intervention group which received 6 sessions (each session 150 minutes in a week) of psycho-educational intervention (N =150), or to a control group which received no intervention (N =150). The patients in both groups completed pretest measures consisting of General Adherence Scale (GAS), Specific Adherence Scale (SAS) and Cardiac Self Efficacy Questionnaire (CSEQ). Participants were reassessed 2-months and 3- months later. Result Multiple regression analysis of the collected data, revealed that both after 2 and 3 months, by enrolling the CDSMRP and Tele-health in the intervention group, enhanced significantly adherence through enhanced self efficacy. Conclusion The CDSMRP and Tele-health, improved the self efficacy of cardiac patients which then enhanced and maintained their adherence.