文章基本信息

标题：Nanometric resolution magnetic resonance imaging methods for mapping functional activity in neuronal networks
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作者：Albert Boretti ; Stefania Castelletto
期刊名称：MethodsX
印刷版ISSN：2215-0161
电子版ISSN：2215-0161
出版年度：2016
卷号：3
页码：297-306
DOI：10.1016/j.mex.2016.04.003
语种：English
出版社：Elsevier
摘要：Highlights • NV in diamond acts as an atomic size optically detectable spin probe. • The probe combines high magnetic field sensitivity and nanometric resolution. • Non-invasive mapping of functional activity in neuronal networks is one application. • Synapse scale resolution ∼10nm but circuit scale FoV>1mm is possible. Abstract This contribution highlights and compares some recent achievements in the use of k-space and real space imaging (scanning probe and wide-filed microscope techniques), when applied to a luminescent color center in diamond, known as nitrogen vacancy (NV) center. These techniques combined with the optically detected magnetic resonance of NV, provide a unique platform to achieve nanometric magnetic resonance imaging (MRI) resolution of nearby nuclear spins (known as nanoMRI), and nanometric NV real space localization. • Atomic size optically detectable spin probe. • High magnetic field sensitivity and nanometric resolution. • Non-invasive mapping of functional activity in neuronal networks.
关键词：Nitrogen vacancy in diamond;Optical detection;Magnetic resonance imaging;Neuronal networks;Nano scale;Super resolution microscopy