文章基本信息

标题：Energy consumption in Hodgkin–Huxley type fast spiking neuron model exposed to an external electric field
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作者：K. Usha ; K. Usha ; M.K. Sreepriya 等
期刊名称：Perspectives in Science
印刷版ISSN：2213-0209
电子版ISSN：2213-0209
出版年度：2016
卷号：8
页码：132-134
DOI：10.1016/j.pisc.2016.04.015
语种：English
出版社：Elsevier
摘要：Summary This paper evaluates the change in metabolic energy required to maintain the signalling activity of neurons in the presence of an external electric field. We have analysed the Hodgkin–Huxley type conductance based fast spiking neuron model as electrical circuit by changing the frequency and amplitude of the applied electric field. The study has shown that, the presence of electric field increases the membrane potential, electrical energy supply and metabolic energy consumption. As the amplitude of applied electric field increases by keeping a constant frequency, the membrane potential increases and consequently the electrical energy supply and metabolic energy consumption increases. On increasing the frequency of the applied field, the peak value of membrane potential after depolarization gradually decreases as a result electrical energy supply decreases which results in a lower rate of hydrolysis of ATP molecules.
关键词：Fast spiking model; Electrical energy supply; Metabolic energy consumption;