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标题：Total flavonoids content and antimicrobial activity of crude extract from leaves of Ficus sycomorus native to Sultanate of Oman
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作者：Sheikha Khamis Al-Matani ; Sheikha Khamis Al-Matani ; Ruqaiya Nasser Said Al-Wahaibi 等
期刊名称：Karbala International Journal of Modern Science
印刷版ISSN：2405-609X
电子版ISSN：2405-609X
出版年度：2015
卷号：1
期号：3
页码：166-171
DOI：10.1016/j.kijoms.2015.11.007
语种：English
出版社：Elsevier
摘要：Abstract The aim of this study was to prepare crude extracts from the leaves of Ficus sycomorus (F. sycomorus) native to Oman, and determine their total flavonoids content as well as their antimicrobial activity. Powdered leaf samples were extracted with methanol by using maceration method. The resulting crude extract was suspended in water and successively extracted with hexane, chloroform, ethyl acetate and butanol solvents, respectively. Total flavonoids of the above extracts were determined by the aluminum chloride method, and antimicrobial activity of the same extracts was assessed by a slightly modified disc diffusion method against different Gram (+ and −) bacterial strains. The highest flavonoids content was found in chloroform crude extract followed by that of hexane, butanol, ethyl acetate, and water extracts, respectively. Tested against four bacterial strains, the extracts showed activity in the range of 0–12 mm, using amoxicillin as standard. The present findings could establish this plant as a potential source of antibiotics.
关键词：Ficus sycomorus ; Maceration extractor; Total flavonoids content; Antimicrobial activity;