文章基本信息

标题：Lupus nephritis: Update on aetiopathogenesis and controversies in classification
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作者：AD Pant
期刊名称：Journal of Pathology of Nepal
印刷版ISSN：2091-0908
出版年度：2014
卷号：4
期号：8
页码：672-676
DOI：10.3126/jpn.v4i8.11596
语种：English
出版社：Association of Clinical Pathologists of Nepal (ACPN)
摘要：Systemic Lupus Erythematosus; a chronic autoimmune disease; is characterized by loss of tolerance against its own antigens and leads to production of autoantibodies and causes formation and deposition of immune complexes in different organs. Recent articles have been trying to unravel the mysteries of SLE. Different theories that have been proposed for the aetiopathogenesis of SLE are a)The circulating immune complex theory, b) The direct binding to endogenous renal antigens theory, and c) binding of antibody to antigens that were previously ‘planted’ into the kidney. DOI: http://dx.doi.org/10.3126/jpn.v4i8.11596 Journal of Pathology of Nepal; Vol.4,No. 8 (2014) 672-676
关键词：Kidney;Immune complex;Systemic lupus erythematosus