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  • 标题:Synthesis Of Garlic Compound Vinyl-Dithiin And Its Derivatives, And Their Anti-Fungal Determination Using Bioautography Methode
  • 作者:C Hanny Wijaya
  • 期刊名称:Jurnal Teknologi Dan Industri Pangan
  • 印刷版ISSN:2087-751X
  • 出版年度:2000
  • 卷号:11
  • 期号:1
  • 页码:48
  • DOI:10.6066/914
  • 语种:English
  • 出版社:Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI
  • 摘要:Improvement on stability, physical characteristics and physiological activities of vinyl-dithiin has been attempted through oxidation and methylation. A bioautography method with Cladosporium cucumerinum showed that the presence of sulphoxide compound increased the anti-fungal activity sharply. Best activity was obtained with the compounds with SSO functional group. Activity was slightly decreased by addition of methyl-group. Stereoisomer also influenced the activity of compound, although not to significantly. Isomer of 3,4-dihidro-3-isopropenil-5-metil-4H-1, 2-ditiin-1-oxide has interesting properties such as crystallized easily, posses weak odor and relatively strong in anti fungal activity. A Simple methallylsynthesis procedure for disufide has been developed using metallyl chloride as starting material.
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